Development of Ferritin-iron Redistribution to Ion Channels (FeRIC) Technology
For decades, researchers have been experimenting with tools used for neural stimulation, modulation, and therapy. A greatly used and helpful tool includes optogenetics, which utilizes light waves to control cells expressing light-sensitive channels. While optogenetics is not an invasive recording technology, due to its dependence on visible light it cannot penetrate deep into the organisms tissue. The purpose of this project is to develop a wireless method similar to optogenetics which can overcome the issues optogenetics encounters. Rather than using light to manipulate neuronal behavior, an electromagnetic field will be provided as the stimulus source. The electromagnetic field will target specific cells that express heat-sensitive proteins, specifically the transient receptor potential channel TRPV1. This method of neural stimulation is ideal as it will reach cells deep within the tissue, and it will not expose the subject to exogenous particles.
Message to Sponsor
- Major: Molecular & Cell Biology- Neurobiology
- Mentor: Chunlei Liu